Enzymes - Mock Test 5

Question 41

An enzyme without cofactor is referred to as

A) Holoenzyme B) Zymogen C) Apoenzyme D) Co-enzyme

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Question 42

The enzyme catalytic activity can be dependent on

A) Covalent bonding B) Cofactors C) Apoenzyme D) Holoenzyme

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Question 43

The binding specificity of an enzyme to a substrate is largely due to

A) Chemical composition of the enzyme B) Chemical composition of the substrate C) Three dimensional structure of the enzyme D) The covalent bonding capacities of the enzyme and substrate

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Question 44

In the ‘induced fit model’ of enzyme function

A) The structure of enzyme and substrate are complementary B) The enzyme undergoes conformation change C) The substrate undergoes conformation change D) There are no conformation changes

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Question 45

The enzyme-substrate interaction does not include

A) Hydrogen bonding B) Covalant bonding C) Electrostatic interactions D) Hydrophobic interactions

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Question 46

The specialized region on an enzyme that interacts with substrate is known as

A) Binding site B) Epitope C) Active site D) Paratope

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Question 47

The following is a competitive type of enzyme inhibitor

A) Acetazolamide B) Disulfiram C) Physostigmine D) Theophylline

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Question 48

Microsomal enzyme induction has one of the following features

A) Takes about one week to develop B) Results in increased affinity of the enzyme for the substrate C) It is irreversible D) Can be used to treat acute drug poisonings

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Question 49

Induction of drug metabolizing enzymes involves

A) A conformational change in the enzyme protein to favour binding of substrate molecules B) Expression of enzyme molecules on the surface of hepatocytes C) Enhanced transport of substrate molecules into hepatocytes D) Increased synthesis of enzyme protein

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Question 50

Which of the following types of drug metabolizing enzymes are inducible

A) Microsomal enzymes B) Nonmicrosomal enzymes C) Both microsomal and nonmicrosomal enzymes D) Mitochondrial enzymes

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