Hormone Metabolism - Mock Test 36

Question 351

In the resting state plasma concentration of cortisol is?

A) 0.4–2.0 µg/100 ml B) 2.0–4.0 µg/100 ml C) 5.0–15.0 µg/100 ml D) 18.0–25.0 µg/100 ml

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Question 352

The defect in adrenal cortex responsible for lack of glucocorticoids and mineralcorticoids is?

A) Androstenedione deficiency B) 17 α -OH progesterone deficiency C) C-21 hydroxylase deficiency D) Testosterone deficiency

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Question 353

Aldosterone synthesis occurs in?

A) Zona reticularis B) Zona fasciculata C) Zona glomerulosa D) Chromaffian cells

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Question 354

A very efficient inhibitor of steroid biosynthesis is?

A) Aminoglutethimide B) Aminoimidazole C) Aminoimidazolesuccinyl carboxamine D) Aminopterin

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Question 355

All mammalian steroid hormones are formed from?

A) Purine B) Pyrimidine C) Cholesterol D) Pyrrole

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Question 356

Cortisol is synthesized in?

A) Zona fasiculata B) Zona glomerulosa C) Zona reticularis D) Chromaffin cells

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Question 357

The predominant glucocorticoid is?

A) Cortisol B) Aldosterone C) Dehydroephiandrosterone D) Androstenedione

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Question 358

Hyperglycemic effect of glucocorticoids is due to?

A) Inactivation of protein phosphatase B) Inactivation of fructose 1,6-biphosphatase C) Stimulation of synthesis of pyruvate carboxylase D) Stimulation of synthesis of eltroxykinase

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Question 359

ACTH induces rise in?

A) Cyclic AMP B) Cyclic GMP C) Calcium D) Magnesium

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Question 360

Excessive secretion of ACTH causes?

A) Cushing’s syndrome B) Addison’s disease C) Myxoedema D) Thyrotoxicosis

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