Hormone Metabolism - Mock Test 9

Question 81

The protein IRS-1 is phosphorylated by?

A) Protein kinase A B) Protein kinase C C) Tyrosine kinase activity of insulin receptor D) Tyrosine kinase activity of IGF-1 receptor

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Question 82

Activation of IRS-1, PI-3 kinase and GRB2 is brought about by?

A) Glucagon B) Insulin C) Prolactin D) IGF-2

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Question 83

Binding of growth hormone to its receptor results in increased transcription of?

A) c-fos gene B) c-myc gene C) p-53 gene D) None of these

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Question 84

Binding of growth hormone to its receptor results in phosphorylation of?

A) JAK-2 B) Growth hormone receptor C) STATs D) All of these

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Question 85

Iodide uptake by thyroid gland is decreased by?

A) Thicyanate B) Thiouracil C) Thiourea D) Methimazole

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Question 86

Urinary excretion of vanillyl madelic acid is increased in?

A) Phaeochromocytoma B) Cushing’s syndrome C) Carcinoid syndrome D) Aldosteronism

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Question 87

Tyrosine hydroxylase is inhibited by?

A) Catecholamines B) α−Methyldopa C) Phenylalanine D) Vanillyl mandelic acid

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Question 88

Dopa decarboxylase is inhibited by?

A) Epinephrine B) Norepinephrine C) α−Methyldopa D) None of these

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Question 89

The rate limiting step in catecholamine synthesis is catalysed by?

A) Phenylalanine hydroxylase B) Tyrosine hydroxylase C) Dopa decarboxylase D) Phenylethanolamine N-methyl transferase

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Question 90

Vasoconstrictor effect of ADH is mediated by?

A) cAMP B) cGMP C) Protein kinase C D) Angiotensin II

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