Nucleic Acids - Mock Test 21

Question 201

Chimeric DNA?

A) Is found in bacteriophages B) Contains unrelated genes C) Has no restriction sites D) Is palindromic

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Question 202

Trials for gene therapy in human beings were first carried out, with considerable success, in a genetic disease called?

A) Cystic fibrosis B) Thalassemia C) Adenosine deaminase deficiency D) Lesch-Nyhan syndrome

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Question 203

Myeloma cells and lymphocytes can be fused by using?

A) Calcium chloride B) Ethidium bromide C) Polyethylene glycol D) DNA polymerase

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Question 204

Hybridoma cells are selected by culturing them in a medium containing?

A) Adenine, guanine, cytosine and thymine B) Adenine, guanine, cytosine and uracil C) Hypoxanthine, aminopterin and thymine D) Hypoxanthine, aminopterin and thymidine

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Question 205

Myeloma cells are lacking in?

A) TMP synthetase B) Formyl transferase C) HGPRT D) All of these

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Question 206

Monoclonal antibodies are prepared by cloning?

A) Myeloma cells B) Hybridoma cells C) T-Lymphocytes D) B-Lymphocytes

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Question 207

For production of eukaryotic protein by recombinant DNA technology in bacteria, the template used is?

A) Eukaryotic gene B) hnRNA C) mRNA D) All of these

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Question 208

The first protein synthesized by recombinant DNA technology was?

A) Streptokinase B) Human growth hormone C) Tissue plasminogen activator D) Human insulin

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Question 209

A particular protein in a mixture can be detected by?

A) Southern blotting B) Northern blotting C) Western blotting D) None of these

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Question 210

An antibody probe is used in?

A) Southern blotting B) Northern blotting C) Western blotting D) None of these

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