Pharmacology - Mock Test 13

Question 121

The primary route of administration of insulin is

A) Intradermal B) Subcutaneous C) Intramuscular D) Intravenous

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Question 122

The insulin receptor is a

A) Ion channel regulating receptor B) Tyrosine protein kinase receptor C) G-protein coupled receptor D) None of the above

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Question 123

Choose the correct statement(s) about actions of insulin

A) It favours translocation of glucose transporters from intracellular site to the plasma membrane B) It enhances transcription of lipoprotein lipase in vascular endothelium C) It increases production of the enzyme glucokinase D) All of the above

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Question 124

Glucose entry into the cells of the following organ/ tissue is highly dependent on the presence of insulin

A) Brain B) Liver C) Adipose tissue D) Kidney tubules

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Question 125

The major limitation of the thiazolidinediones in the treatment of type 2 diabetes mellitus is

A) Frequent hypoglycaemic episodes B) Hyperinsulinemia C) Lactic acidosis D) Low hypoglycaemic efficacy in moderate to severe cases

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Question 126

Action of Insulin <u>does not</u> include the following

A) Facilitation of glucose transport into cells B) Facilitation of glycogen synthesis by liver C) Facilitation of neoglucogenesis by liver D) Inhibition of lipolysis in adipose tissue

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Question 127

Insulin release from pancreatic β cells is augmented by the following <u>except</u>

A) Ketone bodies B) Glucagon C) Vagal stimulation D) Alfa adrenergic agonists

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Question 128

Radioactive iodine is the treatment of choice for the following category of thyrotoxic patients

A) Children B) Young adults with recent oneset of Grave’s disease C) Elderly patients with ischaemic heart disease D) Pregnant women

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Question 129

Propranolol is used in hyperthyroidism

A) As short-term symptomatic therapy till effect of carbimazole develops B) As long-term therapy after subtotal thyroidectomy C) In patients not responding to carbimazole D) To potentiate the effect of radioactive iodine

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Question 130

The most important drawback of radioactive iodine treatment of Grave’s disease is

A) Subsequent hypothyroidism in many patients B) Marked side effect for 1-2 weeks after treatment C) High cost D) Permanent cure cannot be achieved

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