Pharmacology - Mock Test 15

Question 141

Antithyroid drugs exert the following action

A) Inhibit thyroxine synthesis B) Block the action of thyroxine on pituitary C) Block the action of TSH on thyroid D) Block the action of thyroxine on peripheral tissues

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Question 142

Carbimazole acts by inhibiting

A) Iodide trapping B) Oxidation of iodide C) Proteolysis of thyroglobulin D) Synthesis of thyroglobulin protein

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Question 143

The following thyroid inhibitor <u>does not</u> produce goiter when given in over dose

A) Propyl thiouracil B) Carbimazole C) Radioactive iodine D) Sodium thiocyanate

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Question 144

Triiodothyronine is preferred over thyroxine in the treatment of

A) Endemic goiter B) Cretinism C) Papillary carcinoma of thyroid D) Myxoedema coma

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Question 145

Thyroxine therapy is indicated in the following conditions <u>except</u>

A) Euthyroid status with raised TSH level B) Diffuse nontoxic goiter C) Nonfunctional thyroid nodule D) Benign functioning thyroid nodule

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Question 146

Actions of thyroxine include the following <u>except</u>

A) Induction of negative nitrogen balance B) Reduction in plasma cholesterol level C) Fall in plasma free fatty acid level D) Rise in blood sugar level

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Question 147

The most reliable guide to adjustment of thyroxine dose in a patient of hypothyroidism is

A) Pulse rate B) Body weight C) Serum thyroxine level D) Serum TSH level

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Question 148

Metabolic rate of the following organ is <u>not</u> significantly affected by thyroxine

A) Brain B) Heart C) Liver D) Skeletal muscle

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Question 149

Triiodothyronine differs from thyroxine in that

A) It is more avidly bound to plasma proteins B) It has a shorter plasma half life C) It is less potent D) It has a longer latency of action

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Question 150

Trapping of iodide by the following organ/organs is enhanced by thyrotropin

A) Thyroid B) Salivary gland C) Placenta D) All of the above

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