Pharmacology - Mock Test 24

Question 231

Which component of sulfasalazine is responsible for the therapeutic effect in rheumatoid arthritis

A) Intact sulfasalazine molecule B) Sulfapyridine C) 5–aminosalicylic acid D) Both ‘B’ and ‘C’

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Question 232

Which of the following is a disease modifying antirheumatic drug whose active metabolite inhibits the enzyme dihydro-orotate dehydrogenase

A) Leflunomide B) Nimesulide C) Sulfasalazine D) Colchicine

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Question 233

The following antirheumatic drug affords symptomatic relief but does not bring about remission in rheumatoid arthritis

A) Gold sodium thiomalate B) Prednisolone C) Hydroxychloroquine D) Leflunomide

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Question 234

What is true of disease modifying antirheumatic drugs

A) Their beneficial effect is manifest only after 1-3 months of therapy B) The disease does not recurr once they induce remission C) They are to be used life long D) Concurrent use of more than one disease modifying drug is not recommended

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Question 235

Disease modifying antirheumatic drugs are indicated in rheumatoid arthritis

A) In place of NSAIDs in patients who donot tolerate the latter B) Along with NSAIDs in patients with progressive disease C) Only when NSAIDs fail to afford symptomatic relief D) In all patients irrespective of disease status/ concurrent medication

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Question 236

Sulfasalazine is used in the following disease(s)

A) Bacillary dysentery B) Ulcerative colitis C) Rheumatoid arthritis D) Both ‘B’ and ‘C’ are correct

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Question 237

Used as a remission inducing agent in rheumatoid arthritis, hydroxychloroquine

A) Is more effective than chloroquine B) Produces a lower incidence of retinal damage than chloroquine C) Is more effective and more toxic than gold D) Both ‘A’ and ‘B’ are correct

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Question 238

Choose the correct statement(s) about auranofin

A) It is an orally active gold compound B) It is equally effective but less toxic than injected gold-sodium-thiomalate C) Its major adverse effect is dermatitis D) All of the above are correct

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Question 239

Choose the correct statement about use of gold so4⃣ thiomalate in rheumatoid arthritis

A) It affords more rapid symptomatic relief than NSAIDs B) The NSAIDs therapy is discontinued when it is started C) It is used as an alternative to corticosteroids D) thiomalate in rheumatoid arthritis? 1⃣ It affords more rapid symptomatic relief than NSAIDs 2⃣ The NSAIDs therapy is discontinued when it is started 3⃣ It is used as an alternative to corticosteroids

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Question 240

Which of the following is a reserve drug but not a disease modifying drug in rheumatoid arthritis

A) Chloroquine B) Sulfasalazine C) Prednisolone D) Methotrexate

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