Pharmacology - Mock Test 29

Question 281

The distinctive feature of the isoenzyme cyclooxygenase-2 is

A) It is not inhibited by indomethacin B) It is inducible C) It generates cytoprotective prostagladins in gastric mucosa D) It is found only in foetal tissues

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Question 282

Choose the correct statement about nonopioid analgesics

A) All have antiinflammatory property B) All lack dependence producing liability C) All act exclusively at peripheral pain mechanisms D) All inhibit prostaglandin synthesis

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Question 283

The following analgesic lacks antiinflammatory action

A) Paracetamol B) Ibuprofen C) Diclofenac sodium D) Piroxicam

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Question 284

The actions of platelet activating factor include the following except

A) Increased capillary permeability B) Bronchodilatation C) Vasodilatation D) Erosion of gastric mucosa

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Question 285

Prolonged airway hyperreactivity is characteristically caused by

A) Histamine B) Prostaglandin Eâ‚‚ C) Platelet activating factor D) Bradykinin

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Question 286

The following drug is used for cervical priming to facilitate labour

A) Oxytocin B) Clomiphene C) Progesterone D) Prostaglandin Eâ‚‚

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Question 287

Cervical priming with prostaglandin results in

A) Facilitation of sperm movement through cervical canal B) Increased cervical tone C) Softening of cervix D) Increased cervical secretions

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Question 288

Montelukast blocks the action of the following autacoid

A) Prostacyclin B) Platelet activating factor C) Leukotriene Bâ‚„ D) Leukotriene Câ‚„/Dâ‚„

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Question 289

The most prominent action of leukotriene Bâ‚„ is

A) Vasodilatation B) Uterine contraction C) Platelet aggregation D) Chemotaxis of neutrophils and monocytes

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Question 290

Choose the correct statement about cysteinyl leukotrienes (LT-Câ‚„/Dâ‚„)

A) They produce long lasting bronchoconstriction B) They produce sustained rise in blood pressure C) They are responsible for attracting and sequestrating neutrophils at the site of inflammation D) Their production is inhibited by rofecoxib

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