Pharmacology - Mock Test 35

Question 341

Histamine is involved as a mediator in the following pathological condition

A) Delayed hypersensitivity reaction B) Inflammation C) Carcinoid syndrome D) Variant angina

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Question 342

The following statement about histamine is <u>not</u> correct

A) It is the sole mediator of immediate hypersensitivity reaction B) It plays no role in delayed hypersensitivity reaction C) It serves as a neurotransmitter in the brain D) All types of histamine receptors are G protein coupled receptors

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Question 343

Histamine exerts the following actions <u>except</u>

A) Dilatation of large blood vessels B) Dilatation of small blood vessels C) Stimulation of isolated guinea pig heart D) Itching

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Question 344

Autacoids differ from hormones in that

A) Autacoids are involved only in the causation of pathological states B) Autacoids do not have a specific cell/tissue of origin C) Autacoids generally act locally at the site of generation and release D) Both ‘B’ and ‘C’ are correct

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Question 345

Select the drug that suppresses essential tremor, but not parkinsonian tremor

A) Procyclidine B) Propranolol C) Promethazine D) Prochlorperazine

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Question 346

In hyperthyroidism, β adrenergic blockers are used

A) To induce euthyroid state B) As definitive therapy C) For rapid control of certain symptoms while awaiting response to carbimazole D) To reduce basal metabolic rate

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Question 347

In a patient of myocardial infarction, β adrenergic blockers are used with the following aim/aims

A) To reduce the incidence of reinfarction B) To prevent cardiac arrhythmias C) To limit size of the infarct D) All of the above

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Question 348

Select the β adrenergic blocker that is primarily eliminated unchanged by renal excretion

A) Propranolol B) Metoprolol C) Esmolol D) Atenolol

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Question 349

The following is <u>not</u> a feature of cardioselective beta blockers, when compared to propranolol

A) They are ineffective in suppressing muscle tremor B) They are safer in diabetics C) They are less likely to cause bradycardia D) They are less likely to worsen Raynaud’s disease

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Question 350

The basis for use of β-adrenergic blockers in congestive heart failure (CHF) is

A) They exert positive inotropic effect in CHF B) They counteract deleterious effect of sympathetic overactivity on the myocardium C) They exert antiischaemic effect on the heart D) They prevent cardiac arrhythmias

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