Pharmacology - Mock Test 43

Question 421

The following mydriatic does not produce cycloplegia

A) Phenylephrine B) Tropicamide C) Cyclopentolate D) Homatropine

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Question 422

Neostigmine is preferred over physostigmine for treating myasthenia gravis because

A) It is better absorbed orally B) It has longer duration of action C) It has additional direct agonistic action on nicotinic receptors at the muscle end plate D) It penetrates blood-brain barrier

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Question 423

Which of the following mydriatics has the fastest and briefest action

A) Atropine B) Homatropine C) Tropicamide D) Cyclopentolate

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Question 424

Out of two anticholinesterases, drug ‘X’ is a tertiary amine while drug ‘Y’ is a quarternary ammonium compoun4⃣ Then

A) Drug ‘X’ is likely to be more potent than ‘Y’ B) Drug ‘X’ will be more suitable to be used as a miotic C) Drug ‘Y’ will be completely metabolized in the body D) Then?1⃣ Drug ‘X’ is likely to be more potent than ‘Y’ 2⃣ Drug ‘X’ will be more suitable to be used as a miotic 3⃣ Drug ‘Y’ will be completely metabolized in the body

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Question 425

The organophosphates produce irreversible inhibition of cholinesterase because

A) They bind to an allosteric site of the enzyme resulting in unfavourable conformation of esteratic site to bind acetylcholine B) Regeneration time of the phosphorylated enzyme is longer than the turnover time of the enzyme molecules C) Phosphorylation results in rapid degradation of enzyme molecules D) They are neither metabolized nor excreted from the body

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Question 426

Choose the relatively vasicoselective anticholinergic drug used for urinary frequency and urge incontinence due to detrusor instability

A) Pirenzepine B) Oxybutynin C) Oxyphenonium D) Glycopyrolate

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Question 427

Glycopyrrolate is the preferred antimuscarinic drug for use before and during surgery because

A) It is potent and fast acting B) It has no central action C) It has antisecretory and vagolytic actions D) All of the above

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Question 428

The anticholinesterase action of edrophonium is short lasting because termination of its action depends on

A) Dissociation and diffusion of the drug from the enzyme B) Hydrolysis of the drug by the enzyme C) Synthesis of fresh enzyme molecules D) A combination of the above three processes

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Question 429

Children are more susceptible than adults to the following action of atropine

A) Tachycardia producing B) Cycloplegic C) Gastric antisecretory D) Central excitant and hyperthermic

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Question 430

Reactivation of cholinesterase enzyme occurs on hydrolysis of the inhibitor by the same enzyme molecule in case of the following anticholinesterase

A) Edrophonium B) Neostigmine C) Dyflos D) Tacrine

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