Pharmacology - Mock Test 49

Question 481

Interaction between the following pair of drugs can be avoided by making suitable adjustments

A) Levodopa and metoclopramide B) Furosemide and indomethacin C) Tetracyclines and ferrous sulfate D) Clonidine and chlorpromazine

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Question 482

In congestive heart failure patients

A) Volume of distribution of all drugs is increased B) Hepatic clearance of drugs is unaffected C) Orally administered diuretics may not be effective, but the same may work parenterally D) Inotropic action of digoxin is attenuated

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Question 483

The following statement is not correct for uremic patients

A) Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened B) Pethidine can cause seizures C) Diazepam produces exaggerated CNS depression D) Tetracyclines further raise blood urea level

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Question 484

In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance

A) Propranolol B) Digoxin C) Lignocaine D) Verapamil

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Question 485

In patients of hepatic cirrhosis

A) The extent of change in pharmacokinetics of drugs can be predicted from the values of liver function tests B) High doses of furosemide can be safely used C) Metformin is the preferred oral hypoglycaemic D) Disposition of atenolol is not significantly affected

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Question 486

Which of the following is true of ‘placebos’

A) Placebo is a dummy medication B) Placebo is the inert material added to the drug for making tablets C) Placebos do not produce any effect D) All patients respond to placebos

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Question 487

A drug which produces qualitatively different actions when administered through different routes is

A) Phenytoin sodium B) Hydralazine C) Magnesium sulfate D) Nitroglycerine

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Question 488

Drug metabolism can be induced by the following factors except

A) Cigarette smoking B) Acute alcohol ingestion C) Exposure to insecticides D) Consumption charcoal broiled meat

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Question 489

Which of the following adverse drug reactions is due to a specific genetic abnormality

A) Tetracycline induced sunburn like skin lesions B) Quinidine induced thrombocytopenia C) Metoclopramide induced muscle dystonia D) Primaquine induced massive haemolysis

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Question 490

Which racial difference in response to drugs has been mentioned incorrectly below

A) Africans require higher concentration of atropine to dilate pupils B) Black races are more responsive to antihypertensive action of beta blockers C) Japanese are more prone to develop SMON due to halogenated hydroxyquinolines D) Chloramphenicol induced aplastic anaemia is rare among Indians

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