Pharmacology - Mock Test 50

Question 491

The following drug adverse effect is specially noted in men compared to women

A) Tardive dyskinesia due to neuroleptics B) Levodopa induced abnormal movements C) Ampicillin induced loose motions D) Ketoconazole induced loss of libido

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Question 492

The elderly patients are relatively intolerant to

A) Digoxin B) Salbutamol C) Propranolol D) Nifedipine

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Question 493

Which adverse drug effect is more common in children than in adults

A) Isoniazid induced neuropathy B) Chlorpromazine induced muscle dystonia C) Digoxin induced cardiac arrhythmia D) Penicillin hypersensitivity

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Question 494

The pharmacokinetics of drugs in the neonate differs from that in adults, because their

A) Intestinal transit is fast B) Drug metabolizing enzymes are overactive C) Tubular transport mechanisms are not well developed D) Glomerular filtration rate is high

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Question 495

Interindividual variations in equieffective doses of a drug are most marked if it is disposed by

A) Glomerular filtration B) Tubular secretion C) Both glomerular filtration and tubular secretion D) Hepatic metabolism

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Question 496

A fixed dose combination preparation meant for internal use must <u>not</u> contain the following class of drug

A) Thiazide diuretic B) Fluoroquinolone antimicrobial C) Corticosteroid D) H2 blocker

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Question 497

Fixed dose combination formulations are not necessarily appropriate for

A) Drugs administered in standard doses B) Drugs acting by the same mechanism C) Antitubercular drugs D) Antihypertensive drugs

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Question 498

Which of the following statements is not true of fixed dose combination formulations

A) They are more convenient B) Contraindication to one of the components does not contraindicate the formulation C) The dose of any one component cannot be independently adjusted D) The time course of action of the different components may not be identical

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Question 499

A drug which is generally administered in standard doses without the need for dose individualization is

A) Insulin B) Mebendazole C) Prednisolone D) Digoxin

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Question 500

The dose of the following class of drugs has to be adjusted by repeated measurement of the affected physiological parameter

A) Oral contraceptives B) Antiepileptics C) Antidepressants D) Oral anticoagulants

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