Pharmacology - Mock Test 52

Question 511

Higher efficacy of a drug necessarily confers

A) Greater safety B) Therapeutic superiority C) Capacity to produce more intense response D) Cost saving

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Question 512

Which of the following is always true

A) A more potent drug is more efficacious B) A more potent drug is safer C) A more potent drug is clinically superior D) A more potent drug can produce the same response at lower doses

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Question 513

‘Drug efficacy’ refers to

A) The range of diseases in which the drug is beneficial B) The maximal intensity of response that can be produced by the drug C) The dose of the drug needed to produce half maximal effect D) The dose of the drug needed to produce therapeutic effect

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Question 514

Which of the following drugs exhibits ‘therapeutic window’ phenomenon

A) Captopril B) Furosemide C) Diazepam D) Imipramine

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Question 515

When therapeutic effects decline both below and above a narrow range of doses, a drug is said to exhibit

A) Ceiling effect B) Desensitization C) Therapeutic window phenomenon D) Nonreceptor mediated action

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Question 516

The following statement is not true of log dose-response curve

A) It is almost linear except at the ends B) It is a rectangular hyperbola C) It facilitates comparison of different agonists D) It can help in discriminating between competitive and noncompetitive antagonists

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Question 517

Down regulation of receptors can occur as a consequence of

A) Continuous use of agonists B) Continuous use of antagonists C) Chronic use of CNS depressants D) Denervation

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Question 518

A receptor which itself has enzymatic property is

A) Insulin receptor B) Progesterone receptor C) Thyroxine receptor D) Glucagon receptor

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Question 519

The receptor transduction mechanism with the fastest time-course of response effectuation is

A) Adenylyl cyclase-cyclic AMP pathway B) Phospholipase C-IP3: DAG pathway C) Intrinsic ion channel operation D) Protein synthesis modulation

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Question 520

All of the following subserve as intracellular second messengers in receptor mediated signal transduction <u>except</u>

A) Cyclic AMP B) Inositol trisphosphate C) Diacyl glycerols D) G proteins

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