Pharmacology - Mock Test 7

Question 61

The following measure can minimise pituitary-adrenal suppression during long-term corticosteroid therapy

A) Use of betamethasone in place of prednisolone B) Use of prednisolone on alternate days C) Division of the daily dose in three equal 8 hourly doses D) Administration of the total daily dose at bed time

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Question 62

After chronic systemic therapy, withdrawal of corticosteroids should be gradual because

A) Corticosteroids produce psychological dependence B) Abrupt withdrawal may reactivate the underlying disease C) Abrupt withdrawal produces rebound hypertension D) All of the above are correct

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Question 63

Which of the following bones is affected more by glucocorticoid induced osteoporosis

A) Lumber vertebra B) Humerus C) Radius D) Femur

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Question 64

The following adverse effect of corticosteroids is mainly due to their mineralocorticoid action

A) Osteoporosis B) Rise in blood pressure C) ‘Moon face’ D) Increased susceptibility to infection

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Question 65

Systemic corticosteroid therapy is not used routinely and is reserved only for severe cases of

A) Exfoliative dermatitis B) Posterior uveitis C) Acute rheumatic fever D) Hodgkin’s disease

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Question 66

Along with effective antimicrobial therapy, corticosteroids are indicated in the following infective conditions <u>except</u>

A) Tubercular meningitis B) Severe P. carinii pneumonia in AIDS patient C) Herpes simplex keratitis D) Erythema nodosum leprosum

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Question 67

For limiting cerebral edema due to brain tumour, the preferred corticosteroids are betamethasone/dexamethasone because

A) They do not cause Na⁺ and water retention B) They are more potent C) They can be administered intravenously D) They inhibit brain tumours

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Question 68

Corticosteroid therapy is practically mandatory in the following condition

A) Septic shock B) Renal transplant C) Rheumatoid arthritis D) Ulcerative colitis

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Question 69

A patient of chronic bronchial asthma maintained on oral prednisolone 20 mg daily and inhaled salbutamol as required develops chest infection. Which of the following measures is recommended

A) Stop prednisolone B) Reduce prednisolone dose to 5 mg/day C) No change/increase in prednisolone dose D) Substitute prednisolone with inhaled budesonide

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Question 70

Corticosteroid therapy can aggravate the following disorders except

A) Congenital adrenal hyperplasia B) Diabetes mellitus C) Hypertension D) Peptic ulcer

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