Pharmacology - Mock Test 9

Question 81

Adverse consequences of excess mineralocorticoid action include the following except

A) Na⁺ and water retention B) Acidosis C) Aggravation of CHF associated myocardial fibrosis D) Rise in blood pressure

---

No Details

Question 82

Hydrocortisone exerts the following actions

A) Increases both K⁺ and Ca²⁺ excretion B) Decreases both K+ and Ca²⁺ excretion C) Decreases K+ but increases Ca²⁺ excretion D) Increases K+ but decreases Ca²⁺ excretion

---

No Details

Question 83

Aldosterone enhances Na+ reabsorption in renal tubules by

A) Stimulating carbonic anhydrase B) Activating Na⁺ K⁺ ATPase C) Inducing the synthesis of Na⁺ K⁺ ATPase D) Inducing renal prostaglandin synthesis

---

No Details

Question 84

The Na⁺ retaining action of aldosterone is exerted on the

A) Proximal convoluted tubule B) Ascending limb of loop of Henle C) Cortical diluting segment D) Distal convoluted tubule

---

No Details

Question 85

Glucagon release from pancreas is stimulated by

A) High blood glucose level B) Insulin C) Somatostatin D) Adrenaline

---

No Details

Question 86

Select the drug which tends to reverse insulin resistance by increasing cellular glucose transporters

A) Glibenclamide B) Rosiglitazone C) Acarbose D) Prednisolone

---

No Details

Question 87

Guargum limits post-prandial glycaemia by

A) Inhibiting intestinal brush border α-glucosidases B) Slowing carbohydrate absorption from intestine C) Releasing incretins from the intestine D) Promoting uptake of glucose into skeletal muscles

---

No Details

Question 88

The following antidiabetic drug inhibits intestinal brush border α-glucosidase enzymes

A) Acarbose B) Pioglitazone C) Metformin D) Guargum

---

No Details

Question 89

Which of the following is true of acarbose

A) It reduces absorption of glucose from intestines B) It produces hypoglycaemia in normal as well as diabetic subjects C) It limits postprandial hyperglycaemia in diabetics D) It raises circulating insulin levels

---

No Details

Question 90

The following feature disfavours use of oral hypoglycaemics in diabetes mellitus

A) Age at onset of disease over 40 years B) Insulin requirement more than 40 U/day C) Fasting blood sugar level between 100–200 mg/dl D) Associated obesity

---

No Details