Pharmacology - Comprehensive Mock Test 1

Question 1 Medium

The following hypothalamic regulatory hormone is not a peptide

A) Growth hormone release inhibitory hormone B) Prolactin release inhibitory hormone C) Gonadotropin releasing hormone D) Corticotropin releasing hormone

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Question 2 Medium

Leukotriene antagonists are used in bronchial asthma

A) For terminating acute attacks B) As monotherapy in place of β₂ agonists C) As adjuvants to β₂ agonists for avoiding corticosteroids D) As nebulized powder in refractory cases

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Question 3 Medium

The following expectorant acts both directly on the airway mucosa as well as reflexly

A) Potassium iodide B) Guaiphenesin C) Terpin hydrate D) Bromhexine

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Question 4 Medium

Allopurinol has a therapeutic effect in the following conditions except

A) Radiotherapy induced hyperuricaemia B) Hydrochlorothiazide induced hyperuricaemia C) Acute gouty arthritis D) Kala-azar

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Question 5 Medium

Allopurinol is indicated in the following category of chronic gout patients

A) Over producers of uric acid B) Under excretors of uric acid C) Those with tophi and/or renal urate stones D) All of the above

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Question 6 Hard

A 35-year-old male presented with an attack of acute gout. He was treated with a 10 day course of naproxen. His blood uric acid level is high. What future line of treatment is most appropriate

A) No regular medication. Treat attacks of acute gout when they occur with naproxen. B) Regular long-term treatment with naproxen C) Regular long-term treatment with allopurinol D) Start with allopurinol + naproxen for 2 months followed by long-term allopurinol treatment

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Question 7 Easy

Allopurinol does not inhibit the metabolism of

A) 6-Mercaptopurine B) 6-Thioguanine C) Azathioprine D) Theophylline

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Question 8 Easy

Choose the correct statement about allopurinol

A) It is a purine antimetabolite with antineoplastic activity B) It is a competitive inhibitor of xanthine oxidase C) It is inactive itself, but its metabolite alloxanthine is a competitive inhibitor of xanthine oxidase D) Both allopurinol as well as its metabolite alloxanthine are noncompetitive inhibitors of xanthine oxidase

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Question 9 Easy

Allopurinol lowers the plasma concentration of

A) Hypoxanthine B) Xanthine C) Uric acid D) All of the above

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Question 10 Easy

Sulfinpyrazone has the following action(s)

A) Antiplatelet aggregatory B) Uricosuric C) Antiinflammatory D) Both ‘A’ and ‘B’

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