Pharmacology - Comprehensive Mock Test 11

Question 101 Medium

Acetylcholine has no therapeutic application because

A) None of its actions are beneficial in any condition B) Its effects are transient C) It produces wide spread actions affecting many organs D) Both ‘B’ and ‘C’ are correct

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Question 102 Medium

Which of the following secretions is <u>not</u> stimulated by acetylcholine

A) Tear B) Bile C) Pancreatic juice D) Sweat

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Question 103 Medium

The smooth muscle structure that is relaxed by cholinergic drugs is

A) Colon B) Gastric fundus C) Major bronchi D) Bladder trigon

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Question 104 Medium

Cholinergic muscarinic receptor stimulation produces the following effects <u>except</u>

A) Sweating B) Rise in blood pressure C) Bradycardia D) Urination

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Question 105 Medium

The choline ester resistant to both true and pseudocholinesterase is

A) Methacholine B) Bethanechol C) Benzoylcholine D) Butyrylcholine

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Question 106 Medium

Pseudocholinesterase differs from true cholinesterase in that

A) It does not hydrolyse acetylcholine B) It hydrolyses acetylcholine at a slower rate C) It is more susceptible to inhibition by physostigmine D) It is the only form of circulating cholinesterase

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Question 107 Hard

The following cotransmitter is most probably involved in mediating nonadrenergic noncholinergic ( NANC ) relaxation of the gut

A) Neuropeptide Y (NPY) B) Adenosine C) Nitric oxide (NO) D) Kallidin

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Question 108 Medium

The cotransmitter may serve the following function/ functions

A) Regulate the release of the primary transmitter from the nerve ending B) Alter postjunctional action of the primary transmitter C) Itself act as an alternative transmitter D) All of the above

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Question 109 Medium

Tetrodotoxin blocks nerve impulse/junctional transmission by

A) Anticholinergic action B) Depleting acetylcholine C) Blocking Na⁺ channels D) Blocking Ca²⁺ channels

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Question 110 Hard

The sympathetic and parasympathetic systems exert functionally opposite influences on the following parameters <u>except</u>

A) Heart rate B) Atrial refractory period C) Pupil diameter D) Intestinal motility

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