Pharmacology - Comprehensive Mock Test 3

Question 21 Medium

The following antirheumatic drug affords symptomatic relief but does not bring about remission in rheumatoid arthritis

A) Gold sodium thiomalate B) Prednisolone C) Hydroxychloroquine D) Leflunomide

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Question 22 Medium

What is true of disease modifying antirheumatic drugs

A) Their beneficial effect is manifest only after 1-3 months of therapy B) The disease does not recurr once they induce remission C) They are to be used life long D) Concurrent use of more than one disease modifying drug is not recommended

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Question 23 Medium

Disease modifying antirheumatic drugs are indicated in rheumatoid arthritis

A) In place of NSAIDs in patients who donot tolerate the latter B) Along with NSAIDs in patients with progressive disease C) Only when NSAIDs fail to afford symptomatic relief D) In all patients irrespective of disease status/ concurrent medication

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Question 24 Easy

Sulfasalazine is used in the following disease(s)

A) Bacillary dysentery B) Ulcerative colitis C) Rheumatoid arthritis D) Both ‘B’ and ‘C’ are correct

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Question 25 Medium

Used as a remission inducing agent in rheumatoid arthritis, hydroxychloroquine

A) Is more effective than chloroquine B) Produces a lower incidence of retinal damage than chloroquine C) Is more effective and more toxic than gold D) Both ‘A’ and ‘B’ are correct

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Question 26 Easy

Choose the correct statement(s) about auranofin

A) It is an orally active gold compound B) It is equally effective but less toxic than injected gold-sodium-thiomalate C) Its major adverse effect is dermatitis D) All of the above are correct

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Question 27 Medium

Choose the correct statement about use of gold so4⃣ thiomalate in rheumatoid arthritis

A) It affords more rapid symptomatic relief than NSAIDs B) The NSAIDs therapy is discontinued when it is started C) It is used as an alternative to corticosteroids D) thiomalate in rheumatoid arthritis? 1⃣ It affords more rapid symptomatic relief than NSAIDs 2⃣ The NSAIDs therapy is discontinued when it is started 3⃣ It is used as an alternative to corticosteroids

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Question 28 Medium

Which of the following is a reserve drug but not a disease modifying drug in rheumatoid arthritis

A) Chloroquine B) Sulfasalazine C) Prednisolone D) Methotrexate

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Question 29 Medium

The following antiinflammatory analgesic has been cleared for pediatric use

A) Indomethacin B) Ibuprofen C) Ketorolac D) Piroxicam

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Question 30 Medium

Choose the correct statement about topical NSAID preparations

A) They produce high drug levels in the blood by avoiding hepatic first pass metabolism B) They produce high drug levels in the subjacent muscle and joint tissues upto a depth/distance of 10 cm from the site of application C) They elicit symptomatic relief in soft tissue rheumatism mainly by a strong placebo effect D) Interindividual variability in clinical response to these preparations is minimal

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