Pharmacology - Comprehensive Mock Test 4

Question 31 Easy

Choose the correct statement about nefopam

A) It is a nonopioid analgesic which does not inhibit prostaglandin synthesis B) It is an orally active opioid analgesic C) It is an analgesic with potent antiinflammatory activity D) It is a preferential COX-2 inhibitor

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Question 32 Medium

For a patient of peptic ulcer, the safest nonopioid analgesic is

A) Celecoxib B) Diclofenac sodium C) Paracetamol D) Ibuprofen

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Question 33 Medium

Paracetamol has the following advantage(s) over NSAIDs

A) It is the first choice analgesic for majority of osteoarthritis patients B) It can be given safely to all age groups from infants to elderly C) It is not contraindicated in pregnant or breast feeding women D) All of the above

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Question 34 Medium

N-acetyl cysteine is beneficial in acute paracetamol poisoning because

A) It reacts with paracetamol to form a nontoxic complex B) It inhibits generation of the toxic metabolite of paracetamol C) It is a free radical scavenger D) It replenishes hepatic glutathione which in turn binds the toxic metabolite of paracetamol

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Question 35 Medium

Select the drug which inhibits cyclooxygenase in the brain but not at peripheral sites of inflammation

A) Nimesulide B) Paracetamol C) Ketorolac D) Mephenamic acid

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Question 36 Easy

Choose the correct statement about paracetamol

A) It increases uric acid excretion B) It is the most common drug implicated in causing analgesic nephropathy C) In equianalgesic doses it is safer than aspirin D) It stimulates cellular metabolism

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Question 37 Medium

The selective COX-2 inhibitors have the following advantage(s) over the nonselective NSAIDs

A) They are less likely to cause gastric ulcers and their complications B) They are likely to be more effective in rheumatoid arthritis C) They are not likely to produce renal complications D) All of the above

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Question 38 Medium

Among the following, choose the NSAID with the highest COX-2 selectivity

A) Nimesulide B) Nabumetone C) Rofecoxib D) Celecoxib

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Question 39 Easy

The distinctive feature of nimesulide is

A) It does not inhibit prostaglandin synthesis B) It does not cause gastric irritation C) It is usually well tolerated by aspirin intolerant asthma patients D) It is not bound to plasma proteins

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Question 40 Easy

What is true of nimesulide

A) It exerts antiinflammatory action by several mechanisms in addition to cyclooxygenase inhibition B) It is preferred for long-term use in rheumatoid arthritis C) It is contraindicated in aspirin intolerant asthma patients D) All of the above

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