Pharmacology - Comprehensive Mock Test 5

Question 41 Medium

Which of the following is an efficacious antiinflammatory drug but a relatively weak inhibitor of cyclooxygenase

A) Nimesulide B) Paracetamol C) Ketoprofen D) Indomethacin

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Question 42 Medium

The following nonsteroidal antiinflammatory drug is a preferential cyclooxygenase-2 ( COX-2 ) inhibitor

A) Tenoxicam B) Meloxicam C) Diclofenac D) Diclonoxicam

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Question 43 Hard

Which analgesic-antiinflammatory drug is more appropriate in musculo-skeletal disorder where pain is more prominent than inflammation

A) Ibuprofen B) Piroxicam C) Indomethacin D) Nimesulide

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Question 44 Hard

The constellation of adverse effects associated with nonsteroidal antiinflammatory drugs include the following <u>except</u>

A) Sedation B) Gastric irritation C) Fluid retention D) Rashes

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Question 45 Medium

Choose the correct statement about nonsteroidal antiinflammatory drugs (NSAIDs)

A) NSAIDs attenuate hypoglycaemic action of sulfonylureas B) NSAIDs potentiate antihypertensive action of ACE inhibitors C) Serum lithium levels are lowered by concurrent administration of NSAIDs D) Combined therapy with prednisolone and NSAIDs carries higher risk of gastric bleeding

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Question 46 Medium

The patient taking the following non-steroidal antiinflammatory drug should be cautioned not to drive motor vehicle

A) Celecoxib B) Indomethacin C) Naproxen D) Diclofenac sodium

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Question 47 Medium

Which of the following analgesics itself frequently causes headache as a side effect

A) Indomethacin B) Mephenamic acid C) Piroxicam D) Metamizol

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Question 48 Medium

The NSAIDs aggravate the following diseases except

A) Hypertension B) Congestive heart failure C) Peptic ulcer D) Chronic gout

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Question 49 Hard

Phenylbutazone should be used only in patients not responding to other nonsteroidal antiinflammatory drugs (NSAIDs) because

A) It has lower antiinflammatory efficacy than other NSAIDs B) It has potential to cause agranulocytosis C) It has weak analgesic action D) It alters the protein binding and metabolism of many drugs

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Question 50 Medium

The following 5-HT receptor is not a G protein coupled receptor

A) 5-HT₁ B) 5-HT₂ C) 5-HT₃ D) 5-HT₄

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