Pharmacology - Comprehensive Mock Test 7

Question 61 Medium

At therapeutic doses, actions of amphetamine include the following except

A) Prolongation of attention span B) Wakefulness C) Lowering of seizure threshold D) Delaying fatigue

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Question 62 Medium

Ephedrine is similar to adrenaline in the following feature

A) Potency B) Inability to penetrate blood-brain barrier C) Duration of action D) Producing both α and β adrenergic effects

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Question 63 Easy

Dobutamine differs from dopamine in that

A) It does not activate peripheral dopaminergic receptors B) It does not activate adrenergic β receptors C) It causes pronounced tachycardia D) It has good blood-brain barrier penetrability

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Question 64 Medium

The metabolic actions of adrenaline include the following <u>except</u>

A) Glycogenolysis in liver and muscle B) Inhibition of neoglucogenesis in liver C) Lipolysis in adipose tissue D) Release of potassium from liver followed by its uptake

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Question 65 Medium

Adrenaline raises blood glucose level by the following actions <u>except</u>

A) Inducing hepatic glycogenolysis B) Inhibiting insulin secretion from pancreatic β cells C) Augmenting glucagon secretion from pancreatic α cells D) Inhibiting peripheral glucose utilization

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Question 66 Easy

Adrenaline is inactive orally because it is

A) Not absorbed from the gastrointestinal tract B) Destroyed by gastric acid C) Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation D) Taken up by adrenergic nerve endings of the intestinal wall, liver and lungs

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Question 67 Medium

Vasomotor reversal phenomenon after administration of an α adrenergic blocker is seen with

A) Adrenaline B) Noradrenaline C) Isoprenaline D) All of the above drugs

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Question 68 Medium

Low doses of adrenaline dilate the following vascular bed

A) Cutaneous B) Mucosal C) Renal D) Skeletal muscle

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Question 69 Medium

The following action of adrenaline is <u>not</u> mediated by <u>β</u> receptors

A) Dilatation of blood vessels B) Dilatation of pupil C) Bronchodilation D) Renin release from kidney

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Question 70 Medium

The following action of adrenaline is mediated by both α and β receptors producing the same directional effect

A) Cardiac stimulation B) Intestinal relaxation C) Dilatation of pupil D) Bronchodilatation

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