Pharmacology - Comprehensive Mock Test 8

Question 71 Medium

A sympathomimetic amine that acts almost exclusively by releasing noradrenaline from the nerve endings is

A) Ephedrine B) Dopamine C) Isoprenaline D) Tyramine

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Question 72 Medium

The principal process which terminates the action of noradrenaline released from adrenergic nerve ending is

A) Degradation by MAO B) Methylation by COMT C) Axonal uptake D) Extraneuronal uptake

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Question 73 Medium

The following type/types of noradrenaline uptake is blocked by reserpine

A) Axonal uptake B) Granular uptake C) Extraneuronal uptake D) All of the above

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Question 74 Medium

The most efficacious inhibitor of catecholamine synthesis in the body is

A) α-methyl-p-tyrosine B) α-methyldopa C) α-methyl-norepinephrine D) Entacapone

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Question 75 Medium

The rate limiting enzyme in the synthesis of catecholamines is

A) Tyrosine hydroxylase B) Dopa decarboxylase C) Dopamine β-hydroxylase D) Noradrenaline N-methyl transferase

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Question 76 Medium

Which of the following is a noncatecholamine sympathomimetic

A) Adrenaline B) Ephedrine C) Dopamine D) Isoprenaline

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Question 77 Medium

Pralidoxime can reactivate cholinesterase enzyme that has been inactivated by

A) Carbamate anticholinesterases B) Organophosphate anticholinesterases C) Both carbamate and organophosphate anticholinesterases D) Reversible anticholinesterases

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Question 78 Medium

Atropine does not antagonise the following feature of anticholinesterase poisoning

A) Hypotension B) Central excitation C) Muscle paralysis D) Bronchoconstriction

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Question 79 Medium

Which is the most important drug in the treatment of organophosphate poisoning

A) Atropine sulfate B) Pralidoxime C) Diazepam D) Adrenaline

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Question 80 Hard

A suspected case of poisoning has been brought to the casualty with weakness, fainting, involuntary passage of urine and stools, profuse sweating, salivation, watering from nose and eyes. His pulse is 120/min, low volume, BP 90/60 mm Hg, respiration shallow, pupil constricted, muscles flabby with occasional fasciculations. Which is the most likely type of poisoning

A) Belladonna B) Barbiturate C) Anticholinesterase D) Dicophane (DDT)

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