Pharmacology - Comprehensive Mock Test 17

Question 161 Hard

A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a

A) Physiological antagonist B) Competitive antagonist C) Noncompetitive antagonist D) Partial agonist

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Question 162 Hard

A drug ‘R’ producing no response by itself causes the log dose-response curve of another drug ‘S’ to shift to the right in a parallel manner without decreasing the maximal response: Drug ‘R’ is a

A) Partial agonist B) Inverse agonist C) Competitive antagonist D) Noncompetitive antagonist

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Question 163 Medium

The antidotal action of sodium nitrite in cyanide poisoning is based on

A) Physical antagonism B) Chemical antagonism C) Physiological antagonism D) Noncompetitive antagonism

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Question 164 Medium

The antagonism between adrenaline and histamine is called ‘physiological antagonism’ because

A) Both are physiologically present in the body B) They act on physiological receptors C) Both affect many physiological processes D) They have opposite physiological effects

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Question 165 Medium

If the effect of combination of two drugs is equal to the sum of their individual effects, the two drugs are exhibiting

A) Potentiation B) Synergism C) Cross tolerance D) Antagonism

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Question 166 Medium

Compared to the drug named within parenthesis, which of the following drugs has a higher potency but lower efficacy

A) Pethidine (morphine) B) Furosemide (hydrochlorothiazide) C) Diazepam (pentobarbitone) D) Enalapril (captopril)

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Question 167 Medium

The therapeutic index of a drug is a measure of its

A) Safety B) Potency C) Efficacy D) Dose variability

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Question 168 Medium

If the dose-response curves of a drug for producing different actions are widely separated on the dose axis, the drug is

A) Highly potent B) Highly efficacious C) Highly toxic D) Highly selective

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Question 169 Easy

Higher efficacy of a drug necessarily confers

A) Greater safety B) Therapeutic superiority C) Capacity to produce more intense response D) Cost saving

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Question 170 Easy

Which of the following is always true

A) A more potent drug is more efficacious B) A more potent drug is safer C) A more potent drug is clinically superior D) A more potent drug can produce the same response at lower doses

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